Use the Animation panel in Frames mode

Result	Windows
Select/deselect multiple contiguous frames	Shift-click second frame
Select/deselect multiple discontiguous frames	Control-click multiple frames
Paste using previous settings without displaying the dialog box	Alt + Paste Frames command from the Panel pop‑up menu

Use the Brush panel

Result	Windows
Delete brush	Alt-click brush
Rename brush	Double-click brush
Change brush size	Alt + right-click + drag left or right
Decrease/increase brush softness/hardness	Alt + right-click + drag up or down
Select previous/next brush size	, (comma) or. (period)
Select first/last brush	Shift +, (comma) or. (period)
Display precise cross hair for brushes	Caps Lock or Shift + Caps Lock
Toggle airbrush option	Shift + Alt + P

Use the Channels panel

Note:

If you prefer channel shortcuts starting with Ctrl/Command + 1 for red, choose Edit > Keyboard Shortcuts, and select Use Legacy Channel Shortcuts.

Result	Windows
Select individual channels	Ctrl + 3 (red), 4 (green), 5 (blue)
Select composite channel	Ctrl + 2
Load channel as selection	Control-click channel thumbnail, or Alt + Ctrl + 3 (red), 4 (green), 5 (blue)
Add to current selection	Control + Shift-click channel thumbnail
Subtract from current selection	Control + Alt-click channel thumbnail
Intersect with current selection	Control + Shift + Alt-click channel thumbnail
Set options for Save Selection As Channel button	Alt-click Save Selection As Channel button
Create a new spot channel	Control-click Create New Channel button
Select/deselect multiple color-channel selection	Shift-click color channel
Select/deselect alpha channel and show/hide as a rubylith overlay	Shift-click alpha channel
Display channel options	Double-click alpha or spot channel thumbnail
Toggle composite and grayscale mask in Quick Mask mode	~ (tilde)

Use the Clone Source panel

Result	Windows
Show Clone Source (overlays image)	Alt + Shift
Nudge Clone Source	Alt + Shift + arrow keys
Rotate Clone Source	Alt + Shift + < or >
Scale (increase or reduce size) Clone Source	Alt + Shift + [ or ]

Use the Color panel

Result	Windows	macOS
Select background color	Alt-click color in color bar	Option-click color in color bar
Display Color Bar menu	Right-click color bar	Control-click color bar
Cycle through color choices	Shift-click color bar	Shift-click color bar

Use the History panel

Result	Windows
Create a new snapshot	Alt + New Snapshot
Rename snapshot	Double-click snapshot name
Step forward through image states	Control + Shift + Z
Step backward through image states	Control + Alt + Z
Duplicate any image state, except the current state	Alt-click the image state
Permanently clear history (no Undo)	Alt + Clear History (in History panel pop‑up menu)

Use the Info panel

Result	Windows
Change color readout modes	Click eyedropper icon
Change measurement units	Click crosshair icon

Use the Layers panel

Result	Windows
Load layer transparency as a selection	Control-click layer thumbnail
Add to current selection	Control + Shift-click layer thumbnail
Subtract from current selection	Control + Alt-click layer thumbnail
Intersect with current selection	Control + Shift + Alt-click layer thumbnail
Load filter mask as a selection	Control-click filter mask thumbnail
New layer	Control + Shift+ N
New layer via copy	Control + J
New layer via cut	Shift + Control + J
Group layers	Control + G
Ungroup layers	Control + Shift + G
Create/release clipping mask	Control + Alt + G
Select all layers	Control + Alt + A
Merge visible layers	Control + Shift + E
Create new empty layer with dialog box	Alt-click New Layer button
Create new layer below target layer	Control-click New Layer button
Select top layer	Alt +. (period)
Select bottom layer	Alt +, (comma)
Add to layer selection in Layers panel	Shift + Alt + [ or ]
Select next layer down/up	Alt + [ or ]
Move target layer down/up	Control + [ or ]
Merge a copy of all visible layers into target layer	Control + Shift + Alt + E
Merge layers	Highlight layers you want to merge, then Control + E
Move layer to bottom or top	Control + Shift + [ or ]
Copy current layer to layer below	Alt + Merge Down command from the Panel pop‑up menu
Merge all visible layers to a new layer above the currently selected layer	Alt + Merge Visible command from the Panel pop‑up menu
Show/hide this layer/layer group only or all layers/layer groups	Right-click the eye icon
Show/hide all other currently visible layers	Alt-click the eye icon
Toggle lock transparency for target layer, or last applied lock	/ (forward slash)
Edit layer effect/style, options	Double-click layer effect/style
Hide layer effect/style	Alt-double-click layer effect/style
Edit layer style	Double-click layer
Disable/enable vector mask	Shift-click vector mask thumbnail
Open Layer Mask Display Options dialog box	Double-click layer mask thumbnail
Toggle layer mask on/off	Shift-click layer mask thumbnail
Toggle filter mask on/off	Shift-click filter mask thumbnail
Toggle between layer mask/composite image	Alt-click layer mask thumbnail
Toggle between filter mask/composite image	Alt-click filter mask thumbnail
Toggle rubylith mode for layer mask on/off	\ (backslash), or Shift + Alt-click
Select all type; temporarily select Type tool	Double-click type layer thumbnail
Create a clipping mask	Alt-click the line dividing two layers
Rename layer	Double-click the layer name
Edit filter settings	Double-click the filter effect
Edit the Filter Blending options	Double-click the Filter Blending icon
Create new layer group below current layer/layer set	Control-click New Group button
Create new layer group with dialog box	Alt-click New Group button
Create layer mask that hides all/selection	Alt-click Add Layer Mask button
Create vector mask that reveals all/path area	Control-click Add Layer Mask button
Create vector mask that hides all or displays path area	Control + Alt-click Add Layer Mask button
Display layer group properties	Right-click layer group and choose Group Properties, or double-click group
Select/deselect multiple contiguous layers	Shift-click
Select/deselect multiple discontiguous layers	Control-click

Note:

If Kotoeri is your Japanese language input method, the “Toggle rubylith mode for layer mask on/off” shortcut starts an action in Kotoeri. Please switch to another mode (for example, “U.S.”) to enable this shortcut.

Use the Layer Comps panel

Result	Windows
Create new layer comp without the New Layer Comp box	Alt-click Create New Layer Comp button
Open Layer Comp Options dialog box	Double-click layer comp
Rename in-line	Double-click layer comp name
Select/deselect multiple contiguous layer comps	Shift-click
Select/deselect multiple discontiguous layer comps	Control-click

Use the Paths panel

Result	Windows
Load path as selection	Control-click pathname
Add path to selection	Control + Shift-click pathname
Subtract path from selection	Control + Alt-click pathname
Retain intersection of path as selection	Control + Shift + Alt-click pathname
Hide path	Control + Shift + H
Set options for Fill Path with Foreground Color button, Stroke Path with Brush button, Load Path as a Selection button, Make Work Path from Selection button, and Create New Path button	Alt-click button

Use the Swatches panel

Result	Windows
Create new swatch from foreground color	Click in empty area of panel
Set swatch color as background color	Control-click swatch
Delete swatch	Alt-click swatch